Genetic Evidence for Parallel Pathways of Chaperone Activity in the Periplasm of Escherichia coli
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چکیده
منابع مشابه
Genetic evidence for parallel pathways of chaperone activity in the periplasm of Escherichia coli.
The periplasm of Escherichia coli contains many proteins proposed to have redundant functions in protein folding. Using depletion analysis, we directly demonstrated that null mutations in skp and surA, as well as in degP and surA, result in synthetic phenotypes, suggesting that Skp, SurA, and DegP are functionally redundant. The Deltaskp surA::kan combination has a bacteriostatic effect and lea...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 2001
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.183.23.6794-6800.2001